What Is the Mediterra Complex — and What Are Olive Leaf, Pomegranate, and Gynostemma?Updated 2 hours ago
The Codeage Centenarian 100 includes a 900mg proprietary blend called the Mediterra Complex — a combination of three standardized botanical extracts: Olive Leaf Extract, Pomegranate Fruit Extract, and Gynostemma pentaphyllum Extract. Each extract is standardized to a defined percentage of its primary active compounds, ensuring consistency across every serving.
Olive Leaf Extract (Standardized to 25% Oleuropein)
Olive Leaf Extract is derived from the leaves of Olea europaea — the same tree that produces olives and olive oil. It has been used in Mediterranean botanical traditions for centuries and is one of the most widely used botanical extracts in the dietary supplement industry today.
The active compound olive leaf is standardized to is Oleuropein — a naturally occurring polyphenolic compound found in high concentrations in olive leaves and, to a lesser degree, in olive oil and olive fruit. The Mediterra Complex standardizes olive leaf extract to 25% oleuropein, ensuring a defined amount of this active compound per serving.
Pomegranate Fruit Extract (Standardized to 40% Ellagitannins)
Pomegranate Fruit Extract is derived from Punica granatum — the pomegranate, a fruit with deep roots in Mediterranean, Middle Eastern, and South Asian botanical traditions. Pomegranate is one of the most researched fruits in modern nutritional science and is widely used in premium supplement formulations.
The active compounds the pomegranate extract is standardized to are Ellagitannins — a class of polyphenolic compounds found in high concentrations in pomegranate. When metabolized, ellagitannins produce ellagic acid and, in some individuals, urolithins — compounds that have been of significant interest in longevity research. The Mediterra Complex standardizes pomegranate extract to 40% ellagitannins.
You can explore research on pomegranate polyphenols at the National Institutes of Health (NIH).
Gynostemma pentaphyllum Extract — Jiaogulan (Standardized to 80% Gypenosides)
Gynostemma pentaphyllum, commonly known as Jiaogulan, is an herbaceous vine native to China, Japan, Korea, and parts of Southeast Asia. It has been used in traditional Chinese botanical practice for centuries and is sometimes called "the immortality herb" in its regions of origin — a reflection of its long-standing association with wellness and longevity in traditional botanical use, not a medical claim.
The active compounds the extract is standardized to are Gypenosides — a class of saponins (plant-derived compounds) that are unique to Gynostemma pentaphyllum and structurally related to ginsenosides found in ginseng. The Mediterra Complex standardizes Gynostemma extract to 80% gypenosides — one of the highest standardization levels in this botanical category.
Why Are These Three Botanicals Combined?
The Mediterra Complex reflects a botanical tradition rooted in the Mediterranean and East Asian regions — areas associated with long-lived populations in longevity research. The combination of olive leaf, pomegranate, and gynostemma brings together three distinct botanical polyphenol sources — oleuropein, ellagitannins, and gypenosides — each from a different part of the world's longevity botanical tradition.
This product is a dietary supplement. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Codeage formulas are developed with care and may be subject to adjustments over time. We recommend checking the current product label or page for the most up-to-date ingredient and formulation information.
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